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Abeta (1-42) - Amyloid-beta peptide 1-42
Catalog Number: GRP12217
Product Overview
| Product Name | Abeta (1-42) - Amyloid-beta peptide 1-42 |
|---|---|
| Catalog Number | GRP12217 |
| Species/Host | Chicken |
| Reactivity | Human |
| Predicted Reactivity | Bovine, Chicken, Dog, Porcine, Rabbit |
| Tested applications | DOT, ELISA |
| Immunogen | synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A |
Product Properties
| Form/Appearance | Liquid in PBS pH 8.0, 0.02% sodium azide |
|---|---|
| Storage | Store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes. |
| Note | For research use only. |
| Clonality | Polyclonal |
| Purity | Total IgY |
| MW | 4.5 kDa |
Application Notes
| Dilution Range | 1 : 1000 (Dot), 1 : 500 (ELISA) |
|---|---|
| Application Notes | Additional Information: The antibody can detect Abeta(1-42), but does not react with Abeta(1-28) Abeta(1-20) or Abeta(1-17). Background: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067 |
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