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Anti-SARS-CoV-2 Spike Protein (RBD) (RABBIT) Antibody
Catalog Number: GRP13249
| Product Name | Anti-SARS-CoV-2 Spike Protein (RBD) (RABBIT) Antibody |
|---|---|
| Catalog Number | GRP13249 |
| Species/Host | Rabbit |
| Reactivity | Virus |
| Conjugation | Unconjugated |
| Tested applications | ELISA |
| Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of the SARS Coronavirus Spike Protein within the Receptor Binding Domain (RBD). |
| Alternative Names | (click to expand) |
| Form/Appearance | Liquid (sterile filtered) |
|---|---|
| Concentration | 0.99 mg/mL |
| Storage | Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. |
| Note | For research use only. |
| Clonality | Polyclonal |
| Purity | Anti-SARS-CoV-2 Spike affinity purified antibody is directed against SARS Coronavirus 2 Spike protein. The product was purified from monospecific antiserum by immunoaffinity chromatography over SARS CoV-2 Spike resin. BLAST analysis was used to suggest reactivity with related Coronavirus proteins. Cross reactivity with homologues from other sources has not been determined. |
SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2 or COVID-19) is related to SARS-CoV, MERS, and four milder coronaviruses (HKU1, NL63, OC43 and 229E). SARS-CoV-2 is an enveloped positive-strand RNA virus that consists of four structural proteins: spike (S) protein, envelope (E) protein, membrane (M) protein and nucleocapsid (N) protein. The spike protein is the most important surface protein of coronavirus. SARS-CoV-2 has a high affinity binding to human receptor ACE2 (angiotensin-converting enzyme 2) within respiratory epithelial. ACE2 is a membrane-bound aminopeptidase that has a vital role in the cardiovascular and immune systems. Anti-SARS-CoV-2 Spike Protein Antibody is useful for researchers interested in diagnostics and viral research.
| Dilution Range | 1:150,000-1:450,000 |
|---|---|
| Application Notes | Anti-SARS-CoV-2 Spike protein purified antibody has been tested for use in ELISA and shows reactivity to recombinant SARS COV-2, S1 subunit protein and recombinant SARS COV-2 whole spike protein. Specific conditions for reactivity should be optimized by the end user. |
