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Product Overview
Product Name | Bax Polyclonal Antibody |
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Catalog Number | GRP203 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat, Pig, Rabbit |
Conjugation | Unconjugated |
Tested applications | FC, ICC, IF, IHC-P, WB |
Immunogen | KLH conjugated synthetic peptide derived from human Bax (public_immunogen_range: 60-110/192) |
Alternative Names | (click to expand) |
Product Properties
Product Description
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Application Notes
Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400, IF: 1:50-200 |
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