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Cathepsin L Polyclonal Antibody

Catalog Number: GRP407

Product Overview
Product Name Cathepsin L Polyclonal Antibody
Catalog Number GRP407
Species/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications ICC, IF, IHC-P, WB
Immunogen KLH conjugated synthetic peptide derived from mouse capsin L1 proprotein (public_immunogen_range: 80-120/334)
Alternative Names
Product Properties
Form/Appearance Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration 1ug/ul
Storage Store at -20°C for 12 months.
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by Protein A.
Uniprot ID P06797
Entrez 13039
Product Description

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.

Application Notes
Dilution Range WB: 1:300-1000, IHC-P: 1:200-400, IF: 1:50-200
Validation Images
WB of GRP407
IHC-P of GRP407
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