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ERK1 (T203/Y205) + ERK2 (T183/Y185) Polyclonal Antibody

Catalog Number: GRP410

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Datasheet
Product Overview
Product Name ERK1 (T203/Y205) + ERK2 (T183/Y185) Polyclonal Antibody
Catalog Number GRP410
Species/Host Rabbit
Reactivity Human, Mouse, Rat, Bovine
Conjugation Unconjugated
Tested applications IHC-P, WB
Immunogen KLH conjugated synthetic phosphopeptide derived from mouse ERK2 around the phosphorylation site of Thr183 and Tyr 185 (public_immunogen_range: 160-200/358)
Alternative Names (click to expand) ERK; Erk2; MAPK2; PRKM2; Prkm1; C78273; p41mapk; p42mapk; AA47128; AU18647; 93612K14Rik; Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; Mapk1; Mapk
Product Properties
Form/Appearance Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration 1ug/ul
Storage Store at -20°C for 12 months.
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by Protein A.
Uniprot ID P63085
Entrez 26413
Product Description

Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity (By similarity).

Application Notes
Dilution Range WB: 1:300-1000, IHC-P: 1:200-400
Validation Images
WB of GRP410
WB of GRP410
IHC-P of GRP410
IHC-P of GRP410
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