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Estrogen Receptor beta antibody [14C8]

Catalog Number: GRP87

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Datasheet
Product Overview
Product Name Estrogen Receptor beta antibody [14C8]
Catalog Number GRP87
Species/Host Mouse
Reactivity Human, Mouse, Monkey
Conjugation Unconjugated
Tested applications ChIP, DOT, FACS, ICC, IF, IHC-P, WB
Immunogen Amino acids 1-153 of human ER-beta expressed in E. coli.
Alternative Names (click to expand) Estrogen Receptor 2 | Er-Beta | Esr-Beta | Esrb | Estrb | Erb | Nr3A2 | Esr2
Product Properties
Form/Appearance Liquid: PBS
Concentration 1.23 mg/ml
Storage Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Note For research use only.
Isotype IgG2b
Clonality Monoclonal
Purity Protein G purified
Clone ID 14C8
Uniprot ID Q92731
Entrez 2100
Product Description

The human ER-beta is a newly discovered estrogen receptor initially cloned and characterized from testis. The size and structure of ER-beta is very similar to ER-alpha with the ligand and DNA binding domains being highly conserved, while the amino terminus which serves as their transactivation domain has diverged significantly. Similar in function to ER-alpha ER-beta binds to estrogen with a high affinity and regulates estrogen specific gene activation through direct interaction with estrogen response elements (ERE's).

Validation Images
B. Infiltrating lobular carcinoma of the breast.
B. Infiltrating lobular carcinoma of the breast.
Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Estrogen Receptor beta antibody [14C8] (GRP539) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody
Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Estrogen Receptor beta antibody [14C8] (GRP539) diluted at 1:5000. The HRP-conjugated anti-mouse IgG antibody
Estrogen Receptor beta antibody [14C8] detects Estrogen Receptor beta protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human breast carcinoma.Estrogen Receptor beta stained by Estrogen Receptor beta antibody [14C8] (GRP539) dil
Estrogen Receptor beta antibody [14C8] detects Estrogen Receptor beta protein at nucleus by immunohistochemical analysis.Sample: Paraffin-embedded human breast carcinoma.Estrogen Receptor beta stained by Estrogen Receptor beta antibody [14C8] (GRP539) dil
The WB analysis of Estrogen Receptor beta antibody [14C8] was published by Thomas C and colleagues in the journal Breast Cancer Res in 2012 .
The WB analysis of Estrogen Receptor beta antibody [14C8] was published by Thomas C and colleagues in the journal Breast Cancer Res in 2012 .
The WB analysis of Estrogen Receptor beta antibody [14C8] was published by Thomas C and colleagues in the journal Breast Cancer Res in 2012 .
The WB analysis of Estrogen Receptor beta antibody [14C8] was published by Thomas C and colleagues in the journal Breast Cancer Res in 2012 .
The WB analysis of Estrogen Receptor beta antibody [14C8] was published by Thomas C and colleagues in the journal Breast Cancer Res in 2012 .
The WB analysis of Estrogen Receptor beta antibody [14C8] was published by Thomas C and colleagues in the journal Breast Cancer Res in 2012 .
The WB analysis of Estrogen Receptor beta antibody [14C8] was published by Thomas C and colleagues in the journal Breast Cancer Res in 2012 .
The WB analysis of Estrogen Receptor beta antibody [14C8] was published by Thomas C and colleagues in the journal Breast Cancer Res in 2012 .
The WB analysis of Estrogen Receptor beta antibody [14C8] was published by Thomas C and colleagues in the journal Breast Cancer Res in 2012 .
The WB analysis of Estrogen Receptor beta antibody [14C8] was published by Thomas C and colleagues in the journal Breast Cancer Res in 2012 .
The IHC-P analysis of Estrogen Receptor beta antibody [14C8] was published by Samartzis N and colleagues in the journal Reprod Biol Endocrinol in 2012.PMID: 22520060
The IHC-P analysis of Estrogen Receptor beta antibody [14C8] was published by Samartzis N and colleagues in the journal Reprod Biol Endocrinol in 2012.PMID: 22520060
The IHC-P analysis of Estrogen Receptor beta antibody [14C8] was published by Hata S and colleagues in the journal Cancer Med in 2013.PMID: 23930207
The IHC-P analysis of Estrogen Receptor beta antibody [14C8] was published by Hata S and colleagues in the journal Cancer Med in 2013.PMID: 23930207
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