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Product Overview
Product Name | NOX2/gp91phox Polyclonal Antibody |
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Catalog Number | GRP527 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | ICC, IF, IHC-P, WB |
Immunogen | KLH conjugated synthetic peptide derived from human NOX2/gp91phox (public_immunogen_range: 490-540/570) |
Alternative Names | (click to expand) |
Product Properties
Product Description
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
Application Notes
Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400, IF: 1:50-200 |
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