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p75 NGF Receptor Polyclonal Antibody

Catalog Number: GRP207

Product Overview
Product Name p75 NGF Receptor Polyclonal Antibody
Catalog Number GRP207
Species/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications FC, ICC, IF, IHC-P, WB
Immunogen KLH conjugated synthetic peptide derived from rat NGFR (public_immunogen_range: 287-337/425)
Alternative Names
Product Properties
Form/Appearance Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration 1ug/ul
Storage Store at -20°C for 12 months.
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by Protein A.
Uniprot ID P07174
Entrez 24596
Product Description

Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

Application Notes
Dilution Range WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400, IF: 1:50-200
Validation Images
WB of GRP207
IHC-P of GRP207
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