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Product Overview
Product Name | p75 NGF Receptor Polyclonal Antibody |
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Catalog Number | GRP207 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | FC, ICC, IF, IHC-P, WB |
Immunogen | KLH conjugated synthetic peptide derived from rat NGFR (public_immunogen_range: 287-337/425) |
Alternative Names | (click to expand) |
Product Properties
Product Description
Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
Application Notes
Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400, IF: 1:50-200 |
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