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Product Overview
| Product Name | PI3 kinase p85 alpha subunit Antibody |
|---|---|
| Catalog Number | GRP204 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | FC, ICC, IF, IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from human PI3 kinase p85 subunit alpha (public_immunogen_range: 530-580/724) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Application Notes
| Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400, IF: 1:50-200 |
|---|
Validation Images
WB of GRP204
IHC-P of GRP204
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