Availability
- Request Lead Time
- In stock and ready for quick dispatch
- Usually dispatched within 5-10 working days
Product Overview
Product Name | PPAR alpha (Ser12) Polyclonal Antibody |
---|---|
Catalog Number | GRP535 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | IHC-P, WB |
Immunogen | KLH conjugated synthetic phosphopeptide derived from human PPAR alpha around the phosphorylation site of ser12 (public_immunogen_range: 1-15/468) |
Alternative Names | (click to expand) |
Product Properties
Product Description
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Application Notes
Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
---|
Reviews
Write Your Own Review