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Product Overview
Product Name | TDP43 antibody [GT225] |
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Catalog Number | GRP172 |
Species/Host | Mouse |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | ICC, IF, IHC-P, WB |
Immunogen | Recombinant protein encompassing a sequence within the center region of human TDP43. The exact sequence is proprietary. |
Alternative Names | (click to expand) |
Product Properties
Form/Appearance | Liquid: PBS |
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Concentration | 1 mg/ml |
Storage | Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
Note | For research use only. |
Isotype | IgG2b |
Clonality | Monoclonal |
Purity | Affinity purified by Protein G. |
Clone ID | GT225 |
Uniprot ID | Q13148 |
Entrez | 23435 |
Product Description
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]
Application Notes
Dilution Range | WB: 1:500-1:3000,ICC: 1:100-1:1000,IHC-P: 1:100-1:1000 |
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Validation Images
TDP43 antibody [GT225] detects TDP43 protein at nucleus in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. TDP43 antibody [GT225] (GRP624) diluted at 1:200.
TARDBP antibody [GT225] detects TARDBP protein by western blot analysis.A. 30 μg 293T whole cell lysate/extract B. 30 μg A431 whole cell lysate/extract C. 30 μg HeLa whole cell lysate/extract10 % SDS-PAGETARDBP antibody [GT225] (GRP624) dilution:
TDP43 antibody [GT225] detects TDP43 protein at nucleus in mouse brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. TDP43 antibody [GT225] (GRP624) diluted at 1:200.
TARDBP antibody [GT225] detects TARDBP protein by western blot analysis.A. 30 μg BCL-1 whole cell lysate/extract B. 30 μg Raw264.7 whole cell lysate/extract10 % SDS-PAGETARDBP antibody [GT225] (GRP624) dilution: 1:1000
TARDBP antibody [GT225] detects TARDBP protein by western blot analysis.A. 30 μg PC-12 whole cell lysate/extractB. 30 μg Rat2 whole cell lysate/extract10 % SDS-PAGETARDBP antibody [GT225] (GRP624) dilution: 1:1000
Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with TARDBP antibody [GT225] (GRP624) diluted at 1:500.
TDP43 antibody [GT225] detects TDP43 protein by immunofluorescent analysis.Sample: DIV10 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: Nestin stained by Nestin antibody (GRP624) diluted at 1:500.Red: TDP43
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