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Product Overview
Product Name | TEM1/CD248 Polyclonal Antibody |
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Catalog Number | GRP456 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | FC, IHC-P, WB |
Immunogen | KLH conjugated synthetic peptide derived from human TEM 1 (public_immunogen_range: 280-320/757) |
Alternative Names | (click to expand) |
Product Properties
Product Description
The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.
Application Notes
Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400 |
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